Beginning Region 1-3A play at 2-0 for a second straight year, Unicoi improved to 4-1 while the home team slipped to 1-4 (1-1 region).
Lewis carried the football 16 times for 219 yards and three touchdowns, scoring from 61, 36 and 5 yards away.
The visiting Blue Devils, who gained 349 yards on the ground (41 attempts), reeled off 35 straight points after Claiborne tied the game at 7. A 21-point third quarter lifted UC to a 42-7 advantage.
Brett Strother accounted for another 42 yards and a TD on eight attempts. Noah White and Richie Laughren added rushing touchdowns in the third quarter.
The Blue Devils, who welcome Sullivan Central for next week’s homecoming, have won all four meetings against Claiborne by an average of 24.8 points.
RUTLEDGE — The Cyclones spread the wealth as they destroyed the Grizzlies.
Austin Outland had a pair of first-quarter rushing scores while Bryson Rollins and Zach C. Hartley also scored to make it 28-0.
Rollins, a freshman, added a another touchdown in the second quarter as Elizabethton carried a 35-6 advantage into the locker room.
Corey Russell had a rushing and receiving score in the third quarter while Gavin Lowe capped things off with a fourth-quarter score.
Outland finished with 94 yards rushing. Carter Everett threw for 211 yards and a pair of scores.
Elizabethton improved to 2-0 in Region 1-4A and 5-0 overall.
Union County 32
Sullivan East 22
BLUFF CITY — Corbin Patrick had two rushing touchdowns, including a 5-yarder to give the Patriots an early 7-0 lead, but it wasn't enough in the battle of the Patriots.
Mason Hayworth reeled in an 8-yard touchdown pass from Dylan White for Sullivan East's final touchdown and Jayson Baker ran in the two-point conversion. White completed 11 of 19 passes for 132 yards. Hayworth caught three passes for 32 yards, while Blake Scher had two catches for 45 yards and Patrick had two for 40 yards.
Union County nearly doubled East's rushing totals, outgaining the home team 234-119 on the ground.
Johnson County 35
West Greene 7
MOUNTAIN CITY — After the Buffaloes went up 7-0, the Longhorns scored 35 unanswered points thanks to Nathan Lane's 290 all-purpose yards and four touchdowns.
Johnson County's defense held on the second possession, then Lane scored on an 86-yard interception return. He later touched paydirt on a 1-yard run for a 14-7 Johnson County halftime lead.
Zack Eller put the Longhorns ahead on an 76-yard punt return for a touchdown. Lane produced his third touchdown of the game early in the fourth quarter with a 28-yard scamper.
Eller had an interception and Lane raced for a 55-yard touchdown run as he finished with 178 rushing yards.
Tyler Norris and Weston Troop each had 10 tackles to lead Johnson County defensively.
South Greene 34
Sullivan North 27
GREENEVILLE — The Rebels rallied from a two-touchdown deficit in the fourth quarter with 20 unanswered points to defeat the Golden Raiders.
After a late North fumble, Nick Hopson ran in a 5-yard touchdown for the winning score. Prior to that, quarterback Levi Myers rushed for two touchdowns and passes to Tristan Biddy for another. Caleb Parkins had the tying touchdown in the fourth quarter.
North took the early advantage after a blocked punt. Yancey Dolan struck for an 85-yard touchdown and Austin Hartsock later scored on a quarterback sneak for a 21-7 North lead.
Hartsock gave the Golden Raiders the two-touchdown lead in the third quarter with a 7-yard run.
Rossom, N.C. 22
Trinity Knights 20
Edward Newcomb led the rushing total with 86 yards as the Knights fell to their North Carolina opponents.
Austin Tedder finished with 70 rushing yards and Thomas Brown had 50. Titus Brooks accounted for 63 passing yards, while Eli All Good had seven tackles and three assists.